01268nas a2200289 4500000000100000008004100001260001700042653001100059653001100070653001200081653001200093653002600105653000900131653001600140653002200156653001800178100001700196700001300213700002200226700001400248700001900262245011200281300001000393490000700403520055400410022001400964 1977 d c1977 Jul-Sep10aFemale10aHumans10aLectins10aleprosy10aLymphocyte Activation10aMale10aMiddle Aged10aRosette Formation10aT-Lymphocytes1 aKaklamanis E1 aDrouga M1 aKouzoutzakoglou K1 aKaralis D1 aTrichopoulos D00aCellular immunity in patients with leprosy. Circulating T lymphocytes and their response to PHA in leprosy. a241-70 v453 a

The ability of peripheral blood lymphocytes from polar lepromatous (LL), borderline lepromatous (BL) and borderline tuberculoid (BT) patients to transform in vitro in the presence of phytohemagglutinin was found to be significantly reduced. A significant reduction in the percentage and absolute number of T lymphocytes was observed in LL cases. In BL cases the number of T lymphocytes was decreased, but the reduction was proportional to the reduction in the total lymphocyte population was observed only in bacteriologically positive cases.

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