01865nas a2200277 4500000000100000008004100001260004800042653002300090653002600113653001900139653002200158653002400180653001600204653001200220100001600232700001400248700001100262700001200273700001400285245008600299856006600385300001400451490000700465520109000472022002501562 2026 d c09/2026bJaypee Brothers Medical Publishing10aSural nerve biopsy10aPure neuritic variety10aPolyneuropathy10aMultidrug therapy10aDiabetic neuropathy10aCase report10aleprosy1 aBorthakur K1 aMondal SS1 aBasu K1 aNandi A1 aMondal AA00aPure Neuritic Leprosy Masquerading as Diabetic Neuropathy: A Diagnostic Challenge uhttps://apibpj.com/doi/BPJ/pdf/10.5005/jp-journals-10070-8168 a200 - 2020 v133 a
Diabetes mellitus is a well-recognized cause of peripheral neuropathy, often presenting with numbness, paresthesia, and distal limb weakness. However, this common attribution can obscure the diagnosis of more insidious conditions, especially in regions where diseases like leprosy are endemic. Here, we report the case of a 50-year-old woman with longstanding, poorly controlled diabetes mellitus who presented with chronic numbness, distal limb weakness, and a non-healing digital ulcer. Initially suspected to have diabetic neuropathy, further clinical evaluation and histopathological confirmation revealed a diagnosis of pure neuritic type leprosy, a rare and often overlooked form of Hansen’s disease. This case emphasizes the necessity of considering alternative diagnoses, including infectious etiologies, when neuropathic symptoms persist despite standard management, particularly in endemic regions. Early identification and appropriate intervention can significantly alter the disease trajectory, prevent irreversible nerve damage, and improve the quality of life.
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