01613nas a2200313   4500000000100000008004100001260001300042653001000055653000900065653001100074653002900085653003600114653001100150653001800161653001100179653001400190653002400204653000900228653001600237653001900253100001300272700001400285245008000299300000900379490000700388050003200395520085800427022001401285       1988                            d  c1988 Jan10aAdult10aAged10aBiopsy10aCarcinoma, Squamous Cell10aCell Transformation, Neoplastic10aFemale10aFoot Diseases10aHumans10aLeg Ulcer10aLeprosy, Borderline10aMale10aMiddle Aged10aSkin Neoplasms1 aSane S B1 aMehta J M00aMalignant transformation in trophic ulcers in leprosy: a study of 12 cases.  a93-90 v60  aInfolep Library - available3 a<p>Twelve cases of carcinomata arising in Trophic ulcers of Leprosy are presented. Out of these, 10 were on the plantar surface more commonly on the proximal part of foot, one on lower leg and dorsum of foot, and one in an ulcer over the lateral malleolus. Almost all presented with infected growths and regional lymphadenopathy. Three cases presented with advanced disease with fungating inguinal nodes and were fatal. Nine cases underwent below knee amputation under antibiotic cover as a definitive treatment and the lymph nodes were kept under observation. Histologically, all were low grade squamous cell carcinomas. In most cases lymph nodes regressed after removal of primary and in one case lymph nodes were positive for malignancy. This study was conducted at Dr. Bandorawalla Leprosy Hospital, Kondhawa, Pune 22 from the year 1981 to 1987.</p>  a0254-9395