02051nas a2200217   4500000000100000008004100001260005500042653002400097653002300121653002000144653002200164100001500186700002000201700002000221245007800241856012400319300001400443490000700457520134400464022002501808       2026                            d  c09/2026bOvid Technologies (Wolters Kluwer Health)10acoronavirus disease10aHansen’s disease10aLeprosy Disease10aLeprosy reactions1 aHammad RRM1 aAbdel-Alaeem HL1 aKhalaf-Allah SM00aLeprosy disease and its reactions in the era of corona virus disease 2019  uhttps://www.ovid.com/jnls/aamj/pdf/10.4103/azmj.azmj_50_23~leprosy-disease-and-its-reactions-in-the-era-of-corona-virus  a435 - 4390 v243 a<p><strong>Background</strong></p>

<p>Coronavirus disease 2019 (COVID-19) is a serious worldwide health problem that affects direct and indirect however, the implications of COVID-19 co-infection in patients with Hansen’s disease remain uncertain this study aimed to assess the relationship between COVID-19 and leprosy and its reactions.</p>

<p><strong>Patients and methods</strong></p>

<p>This is a descriptive retrospective study conducted on 200 patients presented with different clinical forms of leprosy, according to COVID-19 infection, they divided into two groups, group I=98 COVID-19 positive patients and group II=102 COVID-19 negative patients.</p>

<p><strong>Results</strong></p>

<p>Significant decrease in COVID-19 co-infection among lepromatous leprosy patients with a significant decrease in leprosy reactions. Significant increase in COVID-19 co-infection among tuberculoid patients with a significant increase in leprosy reactions and in number of lepra bacilli detected by slit skin smear among COVID-19 negative patients ( P &lt;0.05). No significant difference between the two groups as regards the classification of leprosy, mode of infection of leprosy, and grade of disability ( P &gt;0.05).</p>

<p><strong>Conclusion</strong></p>

<p>COVID-19 co-infection may enhance leprosy reactions.</p>
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