Background and Objectives:
The study aimed to investigate the occurrence lepra reactions. Additionally, the study sought to examine the correlation between lepra reactions and the spectrum of leprosy.
Methods:
The study utilized a retrospective analysis of cases presenting with lepra reactions. Data on the types of lepra reactions, age and gender distribution, and clinical manifestations were collected and analyzed. Relevant literature and previous studies were reviewed and compared to the findings of the present study.
Results:
The study found that the overall occurrence of lepra reactions was 10.71%, with Type 1 lepra reaction being more prevalent than Type 2 lepra reaction. The age-wise distribution revealed a higher occurrence of T1LR in the 31-40 year age group and T2LR in the 41-50 year age group. Furthermore, lepra reactions were more common in males than females. The clinical manifestations varied for each type of lepra reaction, with specific skin lesions and extracutaneous features being predominant.
Interpretation & Conclusions:
The study concludes that Type 1 lepra reaction was more common in males aged 31-40 years, associated with BT leprosy, and characterized by specific skin lesions and extracutaneous manifestations. In contrast, Type 2 lepra reaction was more prevalent in males aged 41-50 years, linked to LL leprosy, and exhibited distinct clinical features. The findings highlight the need for targeted interventions focusing on education, prevention, early detection, and treatment for leprosy and lepra reactions. Furthermore, the study emphasizes the importance of future multi-centric studies to gain a comprehensive understanding of lepra reactions and their complications.
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