02606nas a2200181   4500000000100000008004100001260001200042653002500054653002800079653002400107100001300131700002500144245013500169856026000304300001200564490000700576520184100583       2026                            d  c05/202610aMedication adherence10alawrence green's theory10aTreatment adherence1 aIndasah 1 aMeilani Erna Horota 00aDeterminants of Compliance with Lawrence Green Theory-Based Leprosy Treatment in Leprosy Patients in Sarmi Regency, Papua Province  uhttps://scholar.google.nl/scholar_url?url=https://www.sjik.org/index.php/sjik/article/download/1242/717&hl=nl&sa=X&d=18386665271482186288&ei=JCEjaoz9IJLwieoPg8Kf8Qk&scisig=ANDmEU4S3mVeUMxvEpnCg6vcnapM&oi=scholaralrt&hist=732gnZIAAAAJ:2504567022825440215:A  a11 - 170 v153 a<p>Leprosy is a chronic infectious disease that requires high adherence to multidrug therapy (MDT) to prevent further complications and transmission. However, the level of patient compliance in undergoing treatment is still a challenge, especially in areas with limited access such as Sarmi Regency, Papua Province. This study aims to analyze the determinants of leprosy treatment adherence based on Lawrence Green's theory, which includes predisposition, enabling, and reinforcing factors. This study uses a quantitative method with the Partial Least Squares - Structural Equation Modeling (PLS-SEM) approach. Data was collected through a questionnaire given to 100 respondents with leprosy in Sarmi Regency. The results of the analysis showed that predisposing factors (knowledge, attitudes, and beliefs) had a significant effect on treatment adherence with a pathway coefficient of 0.434 and a T-Statistic of 12.635. The enabling factor also had a significant effect with a path coefficient of 0.576 and a T-Statistic of 2.87, which shows that the better the access to health services, the higher the patient compliance rate. The reinforcing factor, which includes social support from families and health workers, has a pathway coefficient of 0.250 and a T-Statistic of 3.624, which means that the stronger the support the patient receives, the higher their compliance rate. These findings show that improving patient adherence to leprosy treatment can be achieved through educational strategies that increase patient understanding, improve access to health services, and optimize social support from families and medical personnel. Therefore, community-based interventions and health policies that support ease of access and sustainable education are needed to increase the effectiveness of leprosy treatment in Sarmi Regency.</p>