02356nas a2200241   4500000000100000008004100001260001900042653001100061653001800072653002000090653001800110653001200128100001500140700001600155700002100171700001300192245011300205856005200318300001000370490000700380520171300387022001402100       2026                            d  c03/2026bLepra10aStigma10aMental Health10aQuality of Life10atriple burden10aleprosy1 aElesawy FM1 aAbokersh AA1 aAbd el-Sattar EM1 aShams GM00aThe triple burden of leprosy: A cross-sectional study on stigma, mental health, and quality of life in Egypt  uhttps://leprosyreview.org/article/97/1/20-25103  a1 - 90 v973 a<p><strong>Objective</strong></p>

<p>Leprosy is a lifelong infectious condition that has detrimental physical, psychological, and social implications. Despite meeting the WHO’s elimination target, leprosy continues to impact patients’ lives profoundly in Egypt. The purpose of the research was to measure the quality of life (QoL), mental health status, and perceived stigma among leprosy patients and explore the relationships between these variables.</p>

<p><strong>Methods</strong></p>

<p>A descriptive cross-sectional study was conducted among 108 leprosy patients attending Kafr Elsheikh Dermatology &amp; Leprosy Hospital. Data were collected using standardised tools, including the WHOQOL-BREF, DASS-21, and 6-Item Stigmatisation Scale.</p>

<p><strong>Results</strong></p>

<p>The study revealed poor quality of life (mean total QoL score: 48.34 ± 8.34) and high levels of psychological distress, with 56% of patients experiencing moderate levels of depression, anxiety, and stress. Severe stigmatization was reported by 54% of participants. A significant negative correlation was demonstrated between QoL and mental health status (r =  −0.452,&nbsp;p &lt; 0.001). Unexpectedly, perceived stigma showed a positive correlation with QoL (r = 0.374,&nbsp;p &lt; 0.001).</p>

<p><strong>Conclusions</strong></p>

<p>Leprosy has a significant impact on patients’ quality of life and mental health, emphasizing the importance of integrated treatment approaches that address both the clinical and psychological aspects of the disease. These findings highlight the relevance of holistic care in enhancing patients’ overall well-being and reducing stigma.</p>
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