01429nas a2200241   4500000000100000008004100001260006800042653002200110653002500132100003400157700001900191700001900210700002300229700003300252700002200285700003300307245004600340856007900386300001400465490000700479520067600486022002501162       2021                            d  c03/2021bInstitute of Medico-legal Publications Private Limited10aChildhood leprosy10aImmune dysregulation1 aFlora Ramona Sigit Prakoeswa 1 aBudi Prasetyo 1 aSanti Martini 1 aHardyanto Soebono 1 aMuhammad Yulianto Listiawan 1 aAnang Endaryanto 1 aCita Rosita Sigit Prakoeswa 00aImmune Dysregulation in Childhood Leprosy  uhttps://www.medicopublication.com/index.php/ijfmt/article/view/14725/13334  a2356-23640 v153 a<jats:p>Leprosy is a chronic infection which is caused by Mycobacterium leprae. Leprosy has long been considereda complex disease, in which host and environmental characteristics are as important as the pathogen todetermine disease outcome. Leprosy is an excellent model for examining the immunoregulatory functions.Children are believed to be the most vulnerable group to leprosy infection due to their immature immunity.This review is aimed to summarize the findings of previous studies about immune dysregulation in childhoodleprosy. This study highlighted the plausible maternal-fetal connection which are related in immunedysregulation in childhood leprosy.</jats:p>  a0973-9130, 0973-9122