01749nas a2200229   4500000000100000008004100001260001900042653001600061653002900077653001700106653001200123100001900135700001400154700001400168700001300182245014100195856006300336300000800399490000700407520108000414022002501494       2026                            d  c02/2026bWiley10aCase report10aMycobacterium Infections10aTuberculosis10aleprosy1 aVillanueva CAG1 aOrtiz YRH1 aMojica WP1 aAlbay AB00aType 2 Lepra Reaction Following Antituberculosis Treatment Initiation in an Elderly Male With Coexisting Hansen's Disease: A Case Report  uhttps://onlinelibrary.wiley.com/doi/pdf/10.1002/rcr2.70527  a1-40 v143 a<p>Tuberculosis and leprosy coinfection is increasingly rare even in endemic areas. We report a 70‐year‐old male presenting with fever and malaise. Pulmonary tuberculosis was suggested by chest computed tomography scan and confirmed on polymerase chain reaction testing of bronchial wash specimens. Skin punch biopsies were consistent with lepromatous Hansen's disease. After initiating isoniazid, rifampicin, pyrazinamide and ethambutol, he developed new erythematous patches and plaques on the lower extremities and required supplemental oxygen. Erythema nodosum leprosum was diagnosed. Intravenous hydrocortisone, dapsone and clofazimine were started, and clinical improvement and decreased inflammatory markers followed. The patient was discharged with a 20‐week course of prednisone and multidrug treatment for drug‐susceptible pulmonary tuberculosis and leprosy. Concomitant Hansen's disease should be considered when treating patients for tuberculosis especially in areas where both are prevalent as different long‐term multidrug regimens are required.</p>
  a2051-3380, 2051-3380