01500nas a2200181   4500000000100000008004100001260005500042653004400097653002500141653001400166100001300180700001200193245013700205856026000342300000800602520068300610022002501293       2026                            d  c04/2026bOvid Technologies (Wolters Kluwer Health)10aHereditary Sensory and Motor Neuropathy10aLeprosy, Tuberculoid10aDiagnosis1 aKumar BN1 aSingh M00aBilateral Lower Limb Sensory Motor Neuropathy as the Initial Manifestation of Borderline Tuberculoid Leprosy: A Diagnostic Challenge  uhttps://scholar.google.nl/scholar_url?url=https://journals.lww.com/aoam/_layouts/15/oaks.journals/downloadpdf.aspx%3Fan%3D01244624-990000000-00682&hl=nl&sa=X&d=12109743569688314205&ei=zRvaafuTE8mr6rQP_JWb8QM&scisig=ADi0EEV3cMA6cL2BdoXC_9wcxnud&oi=scholara  a1-33 a<p>Leprosy primarily affects the skin and peripheral nerves, with neuropathy usually accompanying skin lesions. Rarely, neural involvement may precede cutaneous manifestations, leading to diagnostic delay. We report the case of a 36-year-old male presenting with bilateral lower limb sensory motor neuropathy initially attributed to Vitamin B12 deficiency. Despite normalization of B12 levels, symptoms persisted, and subsequent skin changes led to biopsy confirmation of borderline tuberculoid leprosy. This case emphasizes considering Hansen’s disease in patients with unexplained neuropathy, particularly in the endemic regions, even before overt skin lesions appear.</p>
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