01107nas a2200277   4500000000100000008004100001260001300042653001800055653000900073653000900082653001100091653001200102653001300114653001500127653001700142653001600159653001600175100001200191700001200203700001600215245004000231300001100271490000800282520052500290022001400815       1985                            d  c1985 Feb10aBone Diseases10aFoot10aHand10aHumans10aleprosy10aOsteitis10aOsteolysis10aOsteoporosis10aPeriostitis10aRadiography1 aMende B1 aStein G1 aKreysel H W00a[Bone changes in Hansen's disease].  a189-920 v1423 a<p>Bone lesion is a frequent organic manifestation in leprosy. Osseal destructions caused by granulomatous process induced by M. leprae are so-called specific lesions in contrast to non-specific lesions based on nerval or arterial diseases. The specific osseal alterations are characterized by cystic brightenings in roentgenograms while non-specific osseal changes show absorption to bone structure as akroosterolysis and osteoporosis. Typical radiologic findings in different stages of mutilation are demonstrated.</p>  a1438-9029