01252nas a2200289 4500000000100000008004100001260001700042653001200059653001500071653001200086653001200098653001200110653001400122653002700136653001400163100001500177700001500192700001700207700001600224700001500240245005200255300001000307490000700317050003200324520059200356022001400948 1985 d c1985 Apr-Jun10aAnimals10aArmadillos10aDapsone10aFlorida10aleprosy10aLouisiana10aPeptidyl-Dipeptidase A10aVenezuela1 aDhople A M1 aHowell P C1 aWilliams S L1 aZeigler J A1 aStorrs E E00aSerum angiotensin-converting enzyme in leprosy. a282-70 v57 aInfolep Library - available3 a

Serum angiotensin-converting enzyme activity was measured in 91 adult healthy and lepromatous armadillos before inoculation with M. leprae and at necropsises. Mean ACE values were significantly elevated in armadillos with leprosy and the degree of elevation was roughly proportional to the extent of infection. There was also significant difference in the serum ACE levels between Florida and Louisiana armadillos. The dapsone treatment resulted in bringing these levels to normal. Serial assays of serum, ACE provided information on the response of armadillos to dapsone therapy.

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