02211nas a2200265 4500000000100000008004100001260001000042653002100052653001200073653001600085653002100101653001900122100001300141700001400154700001100168700001300179700001500192700001300207245008800220856007500308300000900383490000700392520153200399022001401931 2025 d bLepra10aCommunity stigma10aLeprosy10aIris pearls10aHansen's disease10aEye in leprosy1 aKatoch S1 aChandel T1 aTuli R1 aSharma G1 aChauhan PS1 aMinhas N00aOcular manifestations of leprosy in a tertiary health care centre in Northern India uhttps://leprosyreview.org/article/96/3/20-25069#:~:text=0-,Download,-A a1-110 v963 a

This cross-sectional descriptive study was carried out in the Department of Ophthalmology at Dr RPGMC Tanda Kangra (H.P.) over a one-year time period (2023). The total number of patients studied was 37 (74 eyes), including 16 new cases and 21 old cases.

The M:F ratio was 5:1. Most patients were in age groups 35–50 and >50 (43% each). The most common classification was lepromatous leprosy (51%), followed by borderline leprosy (30%); lepromatous cases had higher ocular disability than other groups.

65% of patients had ocular involvement related to leprosy. Eyelids (42%) were the most commonly affected structures, followed by the cornea (35%) and iris (30%). Eyebrow madarosis was seen in 54% of patients. In the eyelids, ciliary madarosis (34%) and lagophthalmos (8%) were most commonly seen. Corneal involvement included corneal opacities (26%) and 8% patients had active keratitis, 15% had KPs on the endothelium, 11% had SPKs, 9% had vortex keratopathy, and 4% had thickened corneal nerves. 8% of 74 eyes had decreased corneal sensation. 11 eyes (15%) had active uveitis and 4 patients had bilateral uveitis at presentation. Iris atrophy was seen in 30% of eyes. Iris pearls were seen in 7% of eyes. Iris nodules and leproma were seen in only one patient. 19% of patients had dry eyes. Two patients with long-standing lepromatous leprosy had pupillary block glaucoma. 41% patients had grade 0 ocular disability, 27% had grade 1 ocular disability and 32% had grade 2 ocular disability.

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