01606nas a2200217 4500000000100000008004100001260004400042653003400086653002200120653000900142653002600151653003200177100001200209700001400221700001300235700001700248700001100265245012300276520096400399022002501363 2025 d bSpringer Science and Business Media LLC10aLepromatous leprosy diagnosis10aLaryngeal leprosy10aMRSA10aOropharyngeal leprosy10aNasal manifestation leprosy1 aSidam S1 aChavan AG1 aSahoo AK1 aChatterjee T1 aPooja 00aAn Atypical Presentation of Lepromatous Leprosy with Laryngeal Involvement and Secondary MRSA Infection: A Case Report3 a

Lepromatous leprosy is the multibacillary and most severe form of Hansen’s disease, marked by diffuse skin infiltration, nasal involvement, and systemic neuropathy. While nasal and cutaneous signs are well recognized, laryngeal involvement is an uncommon and under-reported manifestation that may lead to diagnostic confusion. We report the case of a 70-year-old male who presented with hoarseness of voice, nasal crusting, palatal lesions, and neurological symptoms. Endoscopic laryngeal examination revealed irregular thickening of the vocal folds and epiglottis. Histopathology and culture from nasal crusts and palatal biopsy confirmed lepromatous leprosy with secondary methicillin-resistant Staphylococcus aureus (MRSA) infection. This case emphasizes the need to consider laryngeal leprosy in patients with chronic hoarseness and mucosal lesions, particularly in endemic areas, and demonstrates the importance of thorough airway examination.

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