01072nas a2200229   4500000000100000008004100001260001700042653001000059653001500069653001900084653001100103653001100114653001200125653000900137100001600146245006700162300001100229490000700240050003200247520054900279022001400828       1987                            d  c1987 Jul-Sep10aAdult10aAmpicillin10aDrug Eruptions10aFemale10aHumans10aleprosy10aSkin1 aPavithran K00aSparing of leprosy macule in ampicillin hypersensitivity rash.  a309-120 v59  aInfolep Library - available3 a<p>A case of tuberculoid leprosy is reported in a middle aged female, who presented with generalised erythematous maculopapular rash which followed ampicillin therapy. In spite of extensive and severe involvement of the skin all over the body by erythema and rash, the hypopigmented patch of leprosy on the face did not show any erythema or rash and stood out more clearly as an island of pale area in the midst of large area of erythema on the face. The possible mechanism of non development of erythema and rash in the patch is discussed.</p>  a0254-9395