01984nas a2200229   4500000000100000008004100001260002900042653002800071653001700099653002900116653004600145653003200191100001400223700001200237700001100249700001500260245010300275856011600378300001200494490000700506520124100513       2025                            d  bHind Kusht Nivaran Sangh10aLeprosy, Multibacillary10aOlder adults10aMulti drug therapy (MDT)10aNecrotising Crescentic Glomerulonephritis10aLeprosy Related Nephropathy1 aBhutani P1 aKumar A1 aDhar M1 aPathania M00aCrescentic Glomerulonephritis in a 65-year-old Male Patient  with Lepromatous Leprosy: Case Report  uhttps://www.ijl.org.in/published-articles/20062025134311/11_Case_Report__Bhutani_et_al__April_June_2025_pdf.pdf  a195-2000 v973 a<p>Leprosy, a chronic infectious disease caused by Mycobacterium leprae, can involve multiple organ systems; however, renal manifestations are uncommon and often under-recognized, especially in the geriatric population. We report a rare case of a 65-year-old male with untreated multibacillary leprosy who presented with acute kidney injury and respiratory distress. Further evaluation uncovered an uncommon glomerular pathology (necrotising crescentic glomerulonephritis) necessitating both immunosuppressive therapy and multi-drug treatment for leprosy. This case highlights the diagnostic and therapeutic challenges in the geriatric population, where age-related changes, comorbidities, and atypical presentations can delay diagnosis. It underscores the importance of maintaining a high index of suspicion for leprosy and its systemic complications—including glomerulonephritis—especially in older patients, where it is often overlooked. Early diagnosis through renal biopsy facilitated appropriate management in this patient. The case emphasizes the importance of integrated, multidisciplinary, and accessible healthcare approaches for older adults with leprosy, particularly those presenting with multi-organ involvement.</p>