00821nas a2200157   4500000000100000008004100001260004400042653001600086653001700102653001200119100001500131245004400146856005500190520040400245022001400649       2025                            d  bSpringer Science and Business Media LLC10aArchaeology10aEpidemiology10aLeprosy1 aRoberts CA00aLeprosy in the Americas before Columbus  uhttps://www.nature.com/articles/s41559-025-02790-93 a<p><em>Mycobacterium lepromatosis</em>&nbsp;genomes associated with 4,000-year-old human skeletons in Chile establish an American origin for this causal agent of leprosy (also known as Hansen’s disease), and point to different evolutionary trajectories and transmission pathways for&nbsp;<em>M.</em>&nbsp;<em>lepromatosis</em>&nbsp;and its sister pathogen&nbsp;<em>Mycobacterium leprae</em>.</p>
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