01153nas a2200241   4500000000100000008004100001260000900042653003500051653003400086653001100120653001200131653001600143653001600159653001700175653002800192100001500220700001900235245006900254300000900323490000700332520055800339022001400897       1988                            d  c198810aDihydrolipoamide Dehydrogenase10aElectron Transport Complex IV10aHumans10aleprosy10aMacrophages10aPeroxidases10aPhagocytosis10aSuccinate Dehydrogenase1 aMaslov A K1 aIushchenko A A00a[Evaluation of the functional state of the leprous macrophages].  a51-40 v503 a<p>Cytochrome oxidase (CCO), peroxidase, succinic dehydrogenase (SDG) and NADH-diaphorase were studied electron-cytochemically in leprous macrophages (LM) of granulomas of patients suffering from lepromatous leprosy. The LM peroxidase activity and location differed, this affecting the completeness of M. leprae phagocytosis. High CCO activity in LM cytoplasm was not a factor essentially influencing M. leprae disintegration. SDG and NADH-diaphorase, locating predominantly in membraneous structures of M. leprae, show low activity in LM cytoplasm.</p>  a0004-1955