01223nas a2200277   4500000000100000008004100001260001300042653002400055653001600079653001200095653003000107653002200137653001100159653002500170653000900195653001600204653001300220653001300233100001600246245004700262300000900309490000700318050003200325520057400357022001400931       1989                            d  c1989 Jan10aAutoimmune Diseases10aClofazimine10aDapsone10aDrug Therapy, Combination10aFollow-Up Studies10aHumans10aLeprosy, lepromatous10aMale10aMiddle Aged10aRifampin10aVitiligo1 aPavithran K00aVitiligo following type II lepra reaction.  a44-80 v61  aInfolep Library - available3 a<p>A middle-aged male with lepromatous leprosy developed bouts of skin lesions of depigmented macules and patches of vitiligo, just following attacks of type II lepra reaction each time. In view of the present concept of autoimmunity playing a role in the pathogenesis of vitiligo as well as lepra reaction, their association in our patient appears to be more than fortuious. The depigmented macules persisted even after regression of skin lesions of leprosy following chemotherapy. The vitiligo macules responded partially to topical and systemic psoralen therapy.</p>  a0254-9395