01654nas a2200205 4500000000100000008004100001260003500042653001200077653001700089653002600106100001300132700001400145700001200159700001200171700001300183245010900196300000600305520112300311022001401434 2024 d bJCDR Research and Publications10aleprosy10aTuberculosis10aAtypical presentation1 aGupta SN1 aChandak M1 aSingh A1 aMadke B1 aJawade S00aAn Unusual Presentation of Co-existence of Leprosy, Anetoderma and Abdominal Tuberculosis: A Case Report a13 aLeprosy and Tuberculosis (TB), both significant mycobacterial infections, often affect populations with lowered specific immunity. TB is a widespread and life-threatening mycobacterial infection. Co-infection of these diseases is uncommon in routine clinical practice, adding complexity to diagnosis and treatment planning. However, instances of co-existence suggest a potential crossimmunity theory. Leprosy, known for its varied presentations, can manifest as an asymptomatic secondary presentation of anetoderma, characterised by elastinolysis-induced loose sac-like appearances. This case report presents a middle-aged man in his late 30s undergoing Anti-Tubercular Treatment (AKT) for abdominal tuberculosis, who presented with signs of Erythema Nodosum Leprosum (ENL) and small asymptomatic atrophied macules on his trunk and back in the Dermatology department. Through comprehensive history, clinical examination, slit skin smear, and biopsy, authors elucidated a rare case of co-infection of leprosy and atypical cutaneous manifestations as anetoderma, concomitant with abdominal tuberculosis. a2249-782X