01159nas a2200181   4500000000100000008004100001260001200042653001500054653002000069653002800089653002100117653000800138653003100146100001400177245002300191520074900214022001400963       2024                            d  c07/202410aNeuropathy10aEarly diagnosis10aMultidrug therapy (MDT)10aElectromyography10aPCR10aHigh-resolution sonography1 aMarques W00aLeprous neuropathy3 a<p><strong>Purpose of review: </strong>Leprosy is still an important cause of neuropathy. Late diagnosis is associated with development of severe nerve impairment.</p>

<p><strong>Recent findings: </strong>early diagnosis and early treatment is essential in order to avoid disability and disease transmission. Recognizing that leprosy is a neurological disease is a fundamental step to the Leprosy zero action proposed by the World Health Organization.</p>

<p><strong>Summary: </strong>leprosy neuropathy manifests as a mononeuropathy or a multiple mononeuropathy with a temperature-dependent distribution. Electromyography, high-resolution sonography serology and PCR help make the diagnosis. Multidrug therapy should be instituted.</p>
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