01022nas a2200181   4500000000100000008004100001260000900042653001100051653002300062653001200085653001500097100001100112245003800123300001000161490000600171520064900177022001400826       1989                            d  c198910aHumans10aImmunity, Cellular10aleprosy10aSkin Tests1 aAyed K00a[Immunologic aspects of leprosy].  a37-400 v73 a<p>Lepromatous leprosy is accompanied by a complex deficit in cell mediated immunity concerning Mycobacterium leprae. The physiological mechanism of this deficit remains unknown. According to some studies there may be, in those suffering from leprosy, a trouble in the macrophage and presentation of antigens. Other studies suggest an increase in the suppressive activity of lymphocytes. Recently some authors emphasized the deficit in the production of interleukin 2. It is difficult, for the time being, to find out whether such immunological abnormalities are primitive or secondary to the accumulation of the bacillus into the organism.</p>  a0001-5938