01471nas a2200313 4500000000100000008004100001260001300042653001000055653001100065653001400076653001100090653002500101653001600126653000900142653001600151653001200167653002500179653002200204653001800226100001200244700001700256700001700273700001700290245008000307300000900387490000700396520074000403022001401143 1989 d c1989 Mar10aAdult10aFemale10aGranuloma10aHumans10aLeprosy, lepromatous10aMacrophages10aMale10aMiddle Aged10aMuscles10aMycobacterium leprae10aPeripheral nerves10aSchwann Cells1 aJob C K1 aKahkonen M E1 aJacobson R R1 aHastings R C00aSingle lesion subpolar lepromatous leprosy and its possible mode of origin. a12-90 v573 a

Three case reports of patients with a single, nodular, subpolar lepromatous skin lesion, one on the left elbow, another on the posterior aspect of the left leg, and the third on the extensor ulnar aspect of the right forearm, are presented. The lesions, clinically and histopathologically, resemble lepromas which develop at the site of experimental inoculation of Mycobacterium leprae in armadillos. These are sites on the body which are likely to be traumatized. With the distinct possibility of the presence of viable M. leprae in the soil of Louisiana and Texas from wild armadillos with the natural disease, it is suggested that these three patients acquired the infection from the environment and had inoculation lepromas.

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