@article{996, keywords = {Adult, Child, Diagnosis, Differential, Female, Humans, Leishmaniasis, Cutaneous, Leishmaniasis, Visceral, leprosy, Macrophages, Male, Neuritis, Time Factors}, author = {Elhassan A M and Ali M S and Zijlstra E and Eltoum I A and Ghalib H W and Ahmed H M}, title = {Post-kala-azar dermal leishmaniasis in the Sudan: peripheral neural involvement.}, abstract = {
Four patients developed post-kala-azar dermal leishmaniasis and neuritis (PKDL) 1 to 6 months following apparently successful treatment of kala-azar. The duration of the lesion varied between 1 month and nearly 5 years. The lesions were macules, papules, or nodules affecting the face, extremities, and trunk. The diagnosis was made by demonstration of the parasite in slit smear and biopsies and by a positive direct agglutination test (DAT). Histologically, the patients were found to have neuritis affecting the cutaneous nerves in the lesion only. The nerves showed a lymphohistiocytic infiltration and occasionally parasites. There was no impairment of sensation. Response to sodium stibogluconate was good. PKDL may simulate leprosy both clinically and pathologically.
}, year = {1992}, journal = {International journal of dermatology}, volume = {31}, pages = {400-3}, month = {1992 Jun}, issn = {0011-9059}, doi = {10.1111/j.1365-4362.1992.tb02668.x}, language = {eng}, }