@article{9810, keywords = {Acquired Immunodeficiency Syndrome, Arthritis, Rheumatoid, Herpesvirus 4, Human, Humans, Immunodiffusion, Immunoelectrophoresis, Immunoglobulin M, Infectious Mononucleosis, Kidney Transplantation, Precipitins, Tumor Virus Infections}, author = {Kim D S and Anthone R and Anthone S and Milgrom F}, title = {Unusual precipitins in pathological human sera.}, abstract = {

In conducting double diffusion gel precipitation tests, unexpected, strong precipitation reactions were noticed between a serum originating from a renal graft recipient and many pathological human sera. The highest frequency of positive reactions were produced by sera of patients with infectious mononucleosis (83%), chronic Epstein-Barr virus infections (72%), rheumatoid arthritis (57%), lepromatous leprosy (57%), and AIDS (44%). The precipitin in these pathological sera was identified as an antibody of IgM variety and the precipitinogen in the transplantation serum was shown to be a thermostable component with beta-globulin mobility. No explanation of the nature of reactions observed can be given at present.

}, year = {1989}, journal = {International archives of allergy and applied immunology}, volume = {89}, pages = {188-90}, month = {1989}, issn = {0020-5915}, doi = {10.1159/000234944}, language = {eng}, }