@article{9807,
  keywords = {Adolescent, Adult, Aged, Autoantibodies, Blood Coagulation Factors, Cardiolipins, Child, DNA, Endocarditis, Bacterial, Enzyme-Linked Immunosorbent Assay, Female, Humans, Infection, leprosy, Lupus Coagulation Inhibitor, Male, Middle Aged, Tuberculosis},
  author = {Santiago M B and COSSERMELLI W and Tuma M F and Pinto M N and Oliveira R M},
  title = {Anticardiolipin antibodies in patients with infectious diseases.},
  abstract = {<p>IgG or IgM anticardiolipin antibodies were present in the sera of 67% of 33 patients with Hansen's disease, in 53% of 30 patients with tuberculosis and in 50% of 16 patients with endocarditis. Despite the high frequency of these antibodies, no patient had a history of thrombosis or abortion. Anti-denatured DNA antibodies were tested in patients with tuberculosis and patients with Hansen's disease. Only in the latter group did we observe a statistically significant association between anticardiolipin and anti-denatured DNA antibodies. Anticardiolipin binding activity, however, could not be inhibited by preincubation of sera with a variable concentration of denatured DNA. These data suggest that: a) Anticardiolipin antibodies in infectious diseases do not necessarily participate in the pathogenesis of thrombotic or obstetric complications; b) Anti-denatured DNA and anticardiolipin antibodies in the population studied do not have a cross-reaction.</p>},
  year = {1989},
  journal = {Clinical rheumatology},
  volume = {8},
  pages = {23-8},
  month = {1989 Mar},
  issn = {0770-3198},
  doi = {10.1007/bf02031064},
  language = {eng},
}