@article{98010,
  keywords = {Infectious Diseases, Microbiology (medical), Parasitology},
  author = {Finardi AJ and Oliveira NGD and Moraes EBD and Batista LCF and Bortolomai BE and Suffys PN and Baptista IMFD},
  title = {Genetic diversity of Mycobacterium leprae in the state of São Paulo, an area of low-leprosy incidence in Brazil},
  abstract = {<p><strong>Background</strong>: Brazil has the second largest number of leprosy cases worldwide, and the state of São Paulo has been considered non-endemic since 2006.</p>

<p><strong>Methods</strong>: We analyzed 16 variable number tandem repeats loci and three single nucleotide polymorphisms loci of Mycobacterium leprae (M. leprae) in 125 clinical isolates from patients in different municipalities in the state.</p>

<p><strong>Results</strong>: The clustering pattern of M. leprae indicated that the transmission of leprosy persisted in the state and included scenarios of intra-extra-familial transmission in areas with low endemicity.</p>

<p><strong>Conclusions</strong>: A significantly active circulation of M. leprae was observed. Therefore, surveillance and control measures must be implemented.</p>
},
  year = {2023},
  journal = {Revista da Sociedade Brasileira de Medicina Tropical},
  volume = {56},
  pages = {1-5},
  publisher = {FapUNIFESP (SciELO)},
  issn = {1678-9849, 0037-8682},
  url = {https://www.scielo.br/j/rsbmt/a/46FySQyktbNVszSCzsnpWGS/?format=pdf&lang=en},
  doi = {10.1590/0037-8682-0612-2022},
  language = {Eng},
}