@article{9783, keywords = {Blister, Cell Count, Humans, Immunohistochemistry, leprosy, Leprosy, Borderline, Leprosy, lepromatous, Leprosy, Tuberculoid, Monocytes, T-Lymphocytes, Helper-Inducer, T-Lymphocytes, Regulatory}, author = {Rangdaeng S and Scollard D M and Suriyanon V and Smith T and Thamprasert K and Theetranont C}, title = {Studies of human leprosy lesions in situ using suction-induced blisters. 1. Cellular components of new, uncomplicated lesions.}, abstract = {
The cellular contents of blisters induced by suction over new, uncomplicated leprosy lesions, and in the skin of cured, control patients, have been examined with enzyme- and immuno-histochemical staining over a period of 4 days. The total cellularity of the blisters varied over a wide range, not correlated with the type of leprosy. Mononuclear cells predominated at all times studied, with nearly equal percentages of monocytes and T lymphocytes. The T-helper: suppressor ratio was significantly greater in BT than in BL and LL lesions at 48 hr. Suction blisters offer a painless, quantitative, reproducible, multiple-sampling method for obtaining cells from the cutaneous infiltrates of leprosy for phenotyping or functional analysis.
}, year = {1989}, journal = {International journal of leprosy and other mycobacterial diseases : official organ of the International Leprosy Association}, volume = {57}, pages = {492-8}, month = {1989 Jun}, issn = {0148-916X}, url = {http://ila.ilsl.br/pdfs/v57n2a07.pdf}, language = {eng}, }