@article{9684,
  keywords = {Animals, Antigens, Bacterial, Antigens, Differentiation, T-Lymphocyte, Cells, Cultured, Cytotoxicity, Immunologic, Epitopes, Mice, Mice, Inbred C57BL, Mycobacterium leprae, Phenotype, Schwann Cells, T-Lymphocytes, Cytotoxic},
  author = {Steinhoff U and Kaufmann S H},
  title = {Specific lysis by CD8+ T cells of Schwann cells expressing Mycobacterium leprae antigens.},
  abstract = {<p>In vitro cultured murine Schwann cells which were devoid of class I and class II gene products of the major histocompatibility complex expressed class I, though not class II, antigens after stimulation with recombinant interferon-gamma. Recombinant IFN-gamma-stimulated Schwann cells after priming with M. leprae were lysed by antigen-specific CD8+ T lymphocytes in vitro. These findings suggest that specific lysis of M. leprae-infected Schwann cells by CD8+ CTL plays a role in leprosy.</p>},
  year = {1988},
  journal = {European journal of immunology},
  volume = {18},
  pages = {969-72},
  month = {1988 Jun},
  issn = {0014-2980},
  doi = {10.1002/eji.1830180622},
  language = {eng},
}