@article{96401,
  keywords = {General Medicine},
  author = {Butlin CR and Maghanoy AA},
  title = {Benefits of high dose clofazimine},
  abstract = {<p>Besides its role in multidrug therapy, clofazimine at higher doses is widely used for relief of Type&nbsp;2 (ENL) reaction in leprosy. There is a lack of evidence from clinical trials regarding indications, optimum regimen and risk/benefit ratio to support published guidelines on its use as an anti-reaction drug. Clinical experience suggests that in adults it is safe at high doses (up to 300&nbsp;mg/day) for limited periods of time but caution is needed with patients of low body weight and in those taking other drugs which may interact.</p>
},
  year = {2021},
  journal = {Leprosy Review},
  volume = {92},
  pages = {427-432},
  publisher = {Lepra},
  issn = {2162-8807},
  url = {https://leprosyreview.org/admin/public/api/lepra/website/getDownload/61b86d62afaac16e5e22b35d},
  doi = {10.47276/lr.92.4.427},
  language = {eng},
}