@article{9569,
  keywords = {Adolescent, Antibody Formation, Child, Child, Preschool, Complement C3, Humans, Immunity, Cellular, Infant, leprosy, Leukocyte Count, Lymphocytes},
  author = {Sehgal V N and Sharma V K and Prakash S K},
  title = {Cell-mediated and humoral immunity in leprosy in children.},
  abstract = {<p>Cell-mediated and humoral immunity were studied in 25 children between 0 and 14 years with leprosy. Cell-mediated immunity was studied in vivo by lepromin and epicutaneous sensitization with dinitrochlorobenzene (DNCB) and T-lymphocytes and their subpopulations (T4 and T8) in the peripheral blood. Humoral immunity was evaluated by B-lymphocyte count and immunoglobulins (IgG, IgM and IgA). Along with complement, component C3 was also measured in the serum. Lepromin (Mitsuda) and DNCB responses were significantly poor in mid-borderline (BB) leprosy. The hematological profile, including T-lymphocytes, their subpopulations, B-lymphocytes, serum immunoglobulins, and C3, were found to be normal in all forms of leprosy. The relatively short duration of disease and the low bacterial load may explain these findings.</p>},
  year = {1990},
  journal = {The Journal of dermatology},
  volume = {17},
  pages = {356-61},
  month = {1990 Jun},
  issn = {0385-2407},
  doi = {10.1111/j.1346-8138.1990.tb01656.x},
  language = {eng},
}