@article{9457, keywords = {Age Factors, Antibodies, Bacterial, Antigens, Bacterial, Democratic Republic of the Congo, Female, Glycolipids, Humans, Incidence, Lepromin, leprosy, Longitudinal studies, Male, Mycobacterium leprae, Predictive Value of Tests, Prevalence, Sex Factors}, author = {Groenen G and Pattyn S R and Ghys P and Tshilumba K and Kuykens L and Colston M J}, title = {A longitudinal study of the incidence of leprosy in a hyperendemic area in Zaire, with special reference to PGL-antibody results. The Yalisombo Study Group.}, abstract = {
Between 1984 and 1988, yearly surveys for leprosy were done among the 1500 people living in a previous leprosy segregation village in Zaire. In 1984 lepromin tests and phenolic glycolipid (PGL) antibody tests were done in a significant part of the population. The prevalence of the disease at that time was 16.1%, the proportion of multibacillary cases was 11.3% overall and 22% among active cases. Prior to 1984, 23% of paucibacillary cases and 56% of multibacillary cases had presented themselves spontaneously to the Leprosy Service. The exposure to the infection is uniform, but there is a suggestion of family clustering of cases. In spite of a rapidly bactericidal treatment of all known cases in 1984 and thereafter, the annual incidence of 0.34% did not decrease during the 4 years of the study. The PGL antibody test did not contribute to the diagnosis, classification or prognosis of the disease.
}, year = {1990}, journal = {International journal of leprosy and other mycobacterial diseases : official organ of the International Leprosy Association}, volume = {58}, pages = {641-50}, month = {1990 Dec}, issn = {0148-916X}, url = {http://ila.ilsl.br/pdfs/v58n4a01.pdf}, language = {eng}, }