@article{94355, author = {Luo W and Lu B and Zhou R and Hu X and Wang J}, title = {Chemical Synthesis of the Trisaccharide Epitope of Phenolic Glycolipid-1 Surface Antigen from Mycobacterium leprae.}, abstract = {
PGL-1 epitope bearing a -aminoethylphenol group was efficiently synthesized by using linear synthetic routes. A method for efficient synthesis of oligosaccharides containing rhamnose rings was developed. The chemistry is flexible and could be used for the synthesis of other PGLs antigens. A biotinylated PGL-1 antigen was synthesized and could be used as a probe for early detection of leprosy.
}, year = {2020}, journal = {The Journal of organic chemistry}, volume = {85}, pages = {10973-10979}, month = {08/2020}, issn = {1520-6904}, doi = {10.1021/acs.joc.0c01088}, language = {eng}, }