@article{9392,
  keywords = {Animals, B-Lymphocytes, leprosy, Lymphoma, Macaca mulatta, Nasal Mucosa, Peripheral nerves, Retroviridae Infections, Simian immunodeficiency virus, Skin, Skin Tests},
  author = {Baskin G B and Gormus B J and Martin L N and Murphey-Corb M and Walsh G P and Meyers W M},
  title = {Pathology of dual Mycobacterium leprae and simian immunodeficiency virus infection in rhesus monkeys.},
  abstract = {<p>Three rhesus monkeys were experimentally inoculated with sooty-mangabey-derived Mycobacterium leprae and were inadvertently infected with the simian immunodeficiency virus (SIV) as well. They died of an immunodeficiency syndrome, and at autopsy all had lesions caused by M. leprae. One monkey was inoculated twice with M. leprae, initially with an inoculum from a sooty mangabey that was not infected with SIV and, subsequently, with an inoculum from a mangabey that was SIV infected. The monkey did not develop clinical lesions and became strongly lepromin skin test (LST) positive after the first inoculation, but became infected with both agents and LST negative following the second inoculation. These observations suggest that SIV-infected rhesus monkeys have an increased susceptibility to M. leprae infection and, by analogy, imply that HIV-infected human beings may have an increased susceptibility as well.</p>
},
  year = {1990},
  journal = {International journal of leprosy and other mycobacterial diseases : official organ of the International Leprosy Association},
  volume = {58},
  pages = {358-64},
  month = {1990 Jun},
  issn = {0148-916X},
  url = {http://ila.ilsl.br/pdfs/v58n2a12.pdf},
  language = {eng},
}