@article{9326,
  keywords = {Antibodies, Bacterial, Antigens, Bacterial, Diagnosis, Differential, Enzyme-Linked Immunosorbent Assay, Humans, Immunoglobulin G, leprosy, Leprosy, lepromatous, Leprosy, Tuberculoid, Molecular Weight, Mycobacterium tuberculosis},
  author = {Das P K and Rambukkana A and Baas J G and Groothuis D G and Halperin M},
  title = {Enzyme-linked immunosorbent assay for distinguishing serological responses of lepromatous and tuberculoid leprosies to the 29/33-kilodalton doublet and 64-kilodalton antigens of Mycobacterium tuberculosis.},
  abstract = {<p>Immunoblot assays for the antibodies to Mycobacterium tuberculosis sonic extracts showed that all serum specimens of 40 lepromatous and of 28 tuberculoid leprosy patients reacted in a significant manner to 29/33-kilodalton (kDa) doublet and 64-kDa antigens, respectively. By using an enzyme-linked immunosorbent assay, we observed a significantly high immunoglobulin G antibody titer to the purified M. tuberculosis 29/33-kDa doublet and 64-kDa antigens in lepromatous and tuberculoid leprosy patients, respectively, as compared with normal subjects and tuberculosis patients. This enzyme-linked immunosorbent assay serology may be useful for distinguishing two polar types of leprosy and for diagnosing leprosy in general.</p>},
  year = {1990},
  journal = {Journal of clinical microbiology},
  volume = {28},
  pages = {379-82},
  month = {1990 Feb},
  issn = {0095-1137},
  url = {https://www.ncbi.nlm.nih.gov/pmc/articles/PMC269615/pdf/jcm00050-0229.pdf},
  language = {eng},
}