@article{9318,
  keywords = {Adolescent, Adult, Aged, Antigens, Bacterial, Child, Enzyme-Linked Immunosorbent Assay, Female, Follow-Up Studies, Glycolipids, Humans, Immunoglobulin M, leprosy, Male, Middle Aged, Mycobacterium leprae, Prognosis},
  author = {Saad M H and Medeiros M A and Gallo M E and Gontijo P P and Fonseca L S},
  title = {IgM immunoglobulins reacting with the phenolic glycolipid-1 antigen from Mycobacterium leprae in sera of leprosy patients and their contacts.},
  abstract = {<p>For the first time in Brazil it was investigated the occurrence of IgM anti-PGL-1 in the sera of household contacts of leprosy patients using the ELISA methodology. The sera of the multibacillary patients showed significantly more immuno-reactivity than from the paucibacillary patients. It was observed a high subclinical infection incidence among household contacts (19.4%). The percentage of leprosy development was 5% (1/21) among the seropositive contact group. This finding suggests that serology could be useful as prognostic test, but for better definition is necessary to test a population from endemic area for long period time.</p>},
  year = {1990},
  journal = {Memorias do Instituto Oswaldo Cruz},
  volume = {85},
  pages = {191-4},
  month = {1990 Apr-Jun},
  issn = {0074-0276},
  url = {http://www.scielo.br/pdf/mioc/v85n2/vol85(f2)_053-056.pdf},
  doi = {10.1590/s0074-02761990000200008},
  language = {eng},
}