@article{9266, keywords = {Adolescent, Adult, Antibodies, Bacterial, Child, Child, Preschool, Enzyme-Linked Immunosorbent Assay, Female, Humans, Immunity, Cellular, Immunoglobulin M, Lepromin, leprosy, Male, Middle Aged, Mycobacterium leprae}, author = {Dhandayuthapani S and Anandan D and Bhatia V N}, title = {ELISA & lepromin skin tests in household contacts of leprosy patients.}, abstract = {

A total of 438 household contacts of leprosy patients and 228 non-contacts were studied for anti-PGL-I antibodies and cell mediated immune response to Mycobacterium leprae using ELISA and lepromin tests. The contacts showed relatively higher positivity to ELISA (29.4%) and lepromin (70.5%) as compared to non-contacts who showed 9.6 and 57 per cent positivity. In contacts as well as non-contacts the seropositivity was not found to be influenced by age and sex. However, seropositivity was higher (39.7%) in the contacts of patients with multibacillary leprosy as compared to contacts (27.7%) of patients with paucibacillary leprosy.

}, year = {1990}, journal = {The Indian journal of medical research}, volume = {91}, pages = {431-6}, month = {1990 Nov}, issn = {0971-5916}, language = {eng}, }