@article{9235, keywords = {Animals, Cytokines, Humans, Immunity, Cellular, Killer Cells, Natural, leprosy, Lymphocyte Activation, Lymphokines, Mice, Phagocytes, T-Lymphocytes}, author = {Kaplan G and Cohn Z A}, title = {Leprosy and cell-mediated immunity.}, abstract = {
The intradermal injection of the purified protein derivative of tuberculin into lepromatous leprosy patients leads to a local cell-mediated immune response and to the extensive destruction of Mycobacterium leprae. This local response also occurs after intradermal injection of recombinant human interleukin-2; when administered over an 8-day period interleukin-2 evokes a systemic cell-mediated immune response and a reduction in the bacillary burden.
}, year = {1991}, journal = {Current opinion in immunology}, volume = {3}, pages = {91-6}, month = {1991 Feb}, issn = {0952-7915}, doi = {10.1016/0952-7915(91)90083-d}, language = {eng}, }