@article{9192,
  keywords = {Adolescent, Adult, Aged, Blood Glucose, Child, Diabetes Mellitus, Dose-Response Relationship, Drug, Female, Follow-Up Studies, Glucocorticoids, Humans, India, leprosy, Male, Middle Aged, Prednisolone, Prospective Studies, Young Adult},
  author = {Papang R and John A S and Abraham S and Rao P S S S},
  title = {A study of steroid-induced diabetes mellitus in leprosy.},
  abstract = {<p>Steroids, while still the most powerful drugs to manage leprosy reactions, predispose some patients to other morbidities such as diabetes, glaucoma, hypertension etc. A prospective cohort study was done in Kolkata, India among leprosy patients in reaction to determine the extent of steroid induced diabetes mellitus (SID). All leprosy patients with type 1 or type 2 reactions or neuritis admitted in 2006 to the Leprosy Mission Hospital in Kolkata, who had no past or current history and whose blood sugars on fasting were <126 mg/dl or postprandial <200 mg/dl were monitored fortnightly while on steroid therapy, estimating blood glucose by a glucometer using standard strips. Of 81 patients, 19 (23.5%) manifested steroid-induced diabetes mellitus. Compared to those who didn't, there were significantly more LL/BL patients with positive BI among SID whose cumulative prednisolone dosage was nearly 9000 mg as compared to half the amount among others. Steroid induced diabetes is a serious complication among leprosy patients treated with prednisolone for reactions requiring careful monitoring for detection and appropriate clinical management.</p>},
  year = {2009},
  journal = {Indian journal of leprosy},
  volume = {81},
  pages = {125-9},
  month = {2009 Jul-Sep},
  issn = {0254-9395},
  url = {http://www.ijl.org.in/July-Sept%202009_PDF%20Files/3_Abst%20(125-130).pdf},
  doi = {10.1136/bmj.c3651},
  language = {eng},
}