@article{9074,
  keywords = {Adult, Ear Diseases, Ear, External, Erythema Nodosum, Glucocorticoids, Humans, Leprostatic Agents, Leprosy, lepromatous, Male, Prednisone, Thalidomide, Thigh},
  author = {Saber M and Bourassa-Fulop C and Bouffard D and Provost N},
  title = {Canadian case report of erythema nodosum leprosum successfully treated with prednisone and thalidomide.},
  abstract = {<p><b>BACKGROUND: </b>Erythema nodosum leprosum (ENL) is a disease rarely encountered in Canada. It is characterized by multiple remissions and recurrences, often requires long-term treatment, and can result in debilitating sequelae.</p><p><b>OBJECTIVE: </b>To promote rapid recognition and adequate therapy for ENL.</p><p><b>METHODS: </b>Case report of a 39-year-old man diagnosed with an ENL. The clinical and histopathologic features, treatment provided, and response to treatment are detailed in this article.</p><p><b>RESULTS: </b>ENL presented itself as painful cutaneous lesions on the face and limbs, bilateral paresthesia of the fourth and fifth fingers, and systemic symptoms. Prednisone 40 mg daily for a week and then 60 mg daily for another week reduced the lesions by 80% and the pain by 50%. Although prednisone 60 mg daily was continued for one more week and then stopped, thalidomide was started at a dose of 300 mg daily for 4 weeks and then reduced gradually, which led to complete resolution.</p><p><b>CONCLUSION: </b>At the 7(1/2)-month follow-up, the patient remained completely asymptomatic.</p>},
  year = {2010},
  journal = {Journal of cutaneous medicine and surgery},
  volume = {14},
  pages = {95-9},
  month = {2010 Mar-Apr},
  issn = {1203-4754},
  doi = {10.2310/7750.2009.08094},
  language = {eng},
}