@article{8874,
  keywords = {Adult, Agranulocytosis, Anemia, Hemolytic, Clofazimine, Dapsone, Drug Therapy, Combination, Female, Humans, Leprostatic Agents, leprosy, Rifampin},
  author = {Silva IM and Oliveira C and Guedes W and Oliveira BB and Oliveira DAP and Guedes Filho G},
  title = {Agranulocytosis induced by multidrug therapy in leprosy treatment: a case report.},
  abstract = {<p>Multidrug therapy (WHO/MDT) in multibacillary leprosy consists of treatment with rifampicin, dapsone and clofazimine. However, adverse effects can cause the patient to abandon treatment. We report on a patient who presented agranulocytosis and hemolytic anemia associated with this treatment regime. We also examined the importance of laboratory exams for diagnosis and follow-up of the patient, and for early detection of adverse effects,with a view to improving adhesion to treatment and contributing to the eradication of Hansen's disease as a public health issue.</p>},
  year = {2009},
  journal = {The Brazilian journal of infectious diseases : an official publication of the Brazilian Society of Infectious Diseases},
  volume = {13},
  pages = {158-60},
  month = {2009 Apr},
  issn = {1678-4391},
  doi = {10.1590/s1413-86702009000200018},
  language = {eng},
}