@article{8768, keywords = {Adolescent, Adult, Aged, Antibodies, Bacterial, Child, Colombia, Contact Tracing, Enzyme-Linked Immunosorbent Assay, Female, Humans, Immunoglobulin G, leprosy, Male, Middle Aged, Mycobacterium leprae, polymerase chain reaction, Risk Factors, Young Adult}, author = {Cardona-Castro N and Beltran-Alzate JC and Romero-Montoya M}, title = {Clinical, bacteriological and immunological follow-up of household contacts of leprosy patients from a post-elimination area - Antioquia, Colombia.}, abstract = {

Follow-up of the household contacts (HHC) of leprosy patients is still the best strategy for early detection of leprosy. HHC from a post-elimination region of Colombia studied in 2001-2002 were re-contacted in 2007. They were tested at both times by clinical examination, bacillary index (BI), PCR from a slit skin smear (SSS) and anti PGL-1 IgM titres. Thirty-two of 61 HHC (52%) were re-contacted. Nine HHC (28%) showed sero-conversion and one had a skin lesion (BI negative, nested PCR positive). Periodic evaluation of HHC can contribute to the detection of infected HHC as well as new and early leprosy cases.

}, year = {2009}, journal = {Memorias do Instituto Oswaldo Cruz}, volume = {104}, pages = {935-6}, month = {2009 Sep}, issn = {1678-8060}, url = {http://www.scielo.br/pdf/mioc/v104n6/21.pdf}, doi = {10.1590/s0074-02762009000600021}, language = {eng}, }