@article{8429, keywords = {Arachidonic Acid, Arachidonic Acids, Eicosapentaenoic Acid, Fatty Acids, Essential, Humans, leprosy, Linoleic Acid, Linoleic Acids, Phospholipids, Stearic Acids}, author = {Wright S and Morse N and Manku M S}, title = {Essential fatty acids in plasma of patients with leprosy.}, abstract = {

We have investigated the fatty-acid composition of plasma phospholipids in 61 patients with leprosy of various clinical types with either a short or long duration of treatment. All patients had significantly decreased levels of linoleic acid and alpha-linoleic acid, the parent fatty acids of the n-6 and n-3 families, respectively. Patients with a treatment duration of more than 6 months had significantly low levels of arachidonic acid and eicosapentaenoic acid compared to controls or to patients with a treatment duration of less than 6 months. There were no differences in the fatty-acid composition between multibacillary patients and paucibacillary patients. We conclude that dietary supplementation with essential fatty acids may be indicated in patients with leprosy, particularly in those with a long treatment duration.

}, year = {1991}, journal = {International journal of leprosy and other mycobacterial diseases : official organ of the International Leprosy Association}, volume = {59}, pages = {271-7}, month = {1991 Jun}, issn = {0148-916X}, url = {http://ila.ilsl.br/pdfs/v59n2a08.pdf}, language = {eng}, }