@article{8395,
  keywords = {Animals, Dose-Response Relationship, Drug, Drug Evaluation, Preclinical, Leprostatic Agents, leprosy, Male, Mice, Mice, Inbred CBA, Microbial Viability, Mycobacterium leprae, Thiocarbamates, Treatment Outcome},
  author = {Urlyapova N G and Yuschenko A A and Daudova A D and Makarov V A},
  title = {Antileprosy activity and preliminary toxicological characteristics of some dialkyldithiocarbamate derivatives.},
  abstract = {<p>Antileprosy activity of dialkyldithiocarbamate derivatives was studied in experiments on mice infected with M. leprae into paw pads. We found that 2-diethyldithiocarbamoyl-3-cyano-5-nitropyridine is the most promising antileprosy agent; it effectively suppresses multiplication of M. leprae and is well tolerated under conditions of chronic animal experiment.</p>},
  year = {2008},
  journal = {Bulletin of experimental biology and medicine},
  volume = {145},
  pages = {446-8},
  month = {2008 Apr},
  issn = {0007-4888},
  doi = {10.1007/s10517-008-0114-6},
  language = {eng},
}