@article{8165, keywords = {Adrenal Cortex Hormones, Aged, Aspirin, Clofazimine, Dapsone, Diagnosis, Differential, Female, Humans, Leprostatic Agents, leprosy, Macrophages, Peritoneal, Mycobacterium lepraemurium, Rifampin}, author = {Gabelle A and Vallat J M and Flageul B and Andre P and Camu W}, title = {[Sensory-motor neuropathy: a slow and misleading case of leprosy].}, abstract = {

The diagnostic process of sensory-motor neuropathies is difficult. Atypical variants and rare etiologies also contribute to delay the diagnosis. We report the case of a 70-year-old woman with slowly progressive asymmetric axonal sensory-motor neuropathy. Leprosy was identified after an eight-year delay. Nerve biopsy was required to establish the diagnosis: electron microscopy revealed debris of Hansen's bacillus in the nerve. Treatment was fully curative after several months. Leprosy is a rare cause of neuropathy in Europeans. Systematic inquiry about travel to endemic areas would be helpful in establishing the diagnosis. In such cases, nerve biopsy is crucial.

}, year = {2008}, journal = {Revue neurologique}, volume = {164}, pages = {964-8}, month = {2008 Nov}, issn = {0035-3787}, doi = {10.1016/j.neurol.2007.11.004}, language = {fre}, }