@article{7780, keywords = {Adolescent, Biomarkers, Case-Control Studies, Child, Child, Preschool, Female, Glucuronidase, Humans, Leprostatic Agents, leprosy, Male}, author = {Nandan D and Venkatesan K and Katoch K and Dayal R S}, title = {Serum beta-glucuronidase levels in children with leprosy.}, abstract = {

A study was undertaken to find out the usefulness of determining the circulating levels of beta-glucuronidase, a lysosomal enzyme in leprosy affected children of less than 15 years of age. The serum enzyme levels were significantly higher in BB/BL patients compared to healthy control children as well as children with skin diseases other than leprosy. Treatment with Multidrug regimen advocated by WHO for multi/paucibacillary leprosy resulted in a significant fall in the serum enzyme levels in BB and BL cases. The findings suggest that serum beta-glucuronidase may be a useful parameter for the activity and extent of pathogenesis in leprosy.

}, year = {2007}, journal = {Leprosy review}, volume = {78}, pages = {243-7}, month = {2007 Sep}, issn = {0305-7518}, url = {https://leprosyreview.org/article/78/3/24-3247}, language = {eng}, }