@article{7689,
  keywords = {Aged, Anti-Bacterial Agents, Clofazimine, Cystamine, Drug Therapy, Combination, Follow-Up Studies, Humans, Leprostatic Agents, leprosy, Male, Middle Aged, Minocycline, Ofloxacin, Rifampin, Time Factors, Treatment Outcome},
  author = {Ozaki M and Ishikawa M},
  title = {[Long-term follow-up of ofloxacin-combined therapy for leprosy patients].},
  abstract = {<p>This reports a long-term follow-up study on clinical effects of ofloxacin (OFLX)-combined therapy to 14 leprosy patients with various types and stages. Combined drugs were diaminodiphenyl sulfone (DDS), rifampicin (RFP) and clofazimine. Clinical evaluation of the treatment after OFLX-combined therapy was remarkable improvement 10 cases, improvement 3 and re-exacerbated after improvement 1 to whom clofazimine and minocycline were prescribed. The evaluation during the follow-up was remarkable improvement 10, improvement 1; three cases died of traffic accident or complications not related to chemotherapy and none of them showed relapse of leprosy. Bacterial negativity after onset of OFLX-combined therapy was achieved in about the same periods as RFP-combined therapy. OFLX-combined therapy was effective and safe. This follow-up study supports the efficacy of clinical guideline for the use of new quinolones published by Japanese leprosy Association.</p>},
  year = {2007},
  journal = {Nihon Hansenbyo Gakkai zasshi = Japanese journal of leprosy : official organ of the Japanese Leprosy Association},
  volume = {76},
  pages = {207-18},
  month = {2007 Sep},
  issn = {1342-3681},
  language = {jpn},
}