@article{7590, keywords = {Adult, AIDS-Related Opportunistic Infections, Antiretroviral Therapy, Highly Active, CD4 Lymphocyte Count, HIV Infections, Humans, Hypersensitivity, Leprostatic Agents, Leprosy, Borderline, Leprosy, Tuberculoid, Male, Skin, Syndrome}, author = {Kharkar V and Bhor U and Mahajan S and Khopkar U}, title = {Type I lepra reaction presenting as immune reconstitution inflammatory syndrome.}, abstract = {

Immune reconstitution inflammatory syndrome (IRIS) is an unusual inflammatory reaction due to infectious and non-infectious causes occurring in human Immunodeficiency virus (HIV)-infected patients. IRIS occurs after the initiation of antiretroviral therapy. There are no reports of type I lepra reaction due to IRIS in published literature from India. We report two cases of HIV-infected males who presented with borderline tuberculoid leprosy in type 1 reaction after the initiation of highly active antiretroviral treatment (HAART). Case 1 presented with multiple, tender, erythematous and hypoesthetic plaques on the trunk and extremities after 3 months of antiretroviral therapy. In case 2, type I lepra reaction was observed 2 months after the initiation of HAART.

}, year = {2007}, journal = {Indian journal of dermatology, venereology and leprology}, volume = {73}, pages = {253-6}, month = {2007 Jul-Aug}, issn = {0973-3922}, language = {eng}, }