@article{720, keywords = {Adolescent, Adult, Antibodies, Bacterial, Child, Child, Preschool, Female, Humans, Immunoglobulin M, Indonesia, Infant, Latex Fixation Tests, leprosy, Male, Mass Screening, Middle Aged, Mycobacterium leprae, Prevalence, Prospective Studies, Seroepidemiologic Studies, Suburban Health}, author = {Hatta M and Izumi S and Klatser P R}, title = {Evaluation of the Mycobacterium leprae particle agglutination (MLPA) test as a tool in the epidemiology of leprosy in high prevalence village in South Sulawesi, Indonesia.}, abstract = {
This study reports on the usefulness of an IgM phenolic glycolipid-1 (PGL-1) Mycobacterium leprae particle agglutination (MLPA) test for serodiagnosis of leprosy in a prospective longitudinal community survey in a high prevalence village in South Sulawesi, Indonesia, IgM PGL-1 MLPA has simple and limited value as a screening method for detection of transmission of leprosy in the community. Many normal persons in the community in a high prevalence area had increased IgM anti PGL-1 antibodies, presumably as a consequence of early subclinical infection. In conclusion, this study demonstrated that the MLPA test can only reliably detect anti-PGL-1 antibodies in the community and may be useful for follow-up study of subclinical infection of leprosy among individuals living the an endemic area.
}, year = {1995}, journal = {The Southeast Asian journal of tropical medicine and public health}, volume = {26}, pages = {631-5}, month = {1995 Dec}, issn = {0125-1562}, language = {eng}, }