@article{7062,
  keywords = {Adolescent, Adult, Animals, Asia, Bacterial Proteins, Brazil, Female, genotype, Humans, Japan, leprosy, Male, Mice, Mice, Nude, Middle Aged, Mycobacterium leprae, Polymorphism, Single Nucleotide, Repetitive Sequences, Nucleic Acid, Sigma Factor},
  author = {Matsuoka M and Lopez Roa RI and Budiawan T and Kyaw K and Chae G},
  title = {Genotypic analysis of Mycobacterium leprae isolates from Japan and other Asian countries reveals a global transmission pattern of leprosy.},
  abstract = {<p>The genotype of single-nucleotide polymorphism type 3, CTC, at positions 14676, 164275, and 2935685, along with four copies of 6 bp repeats in the rpoT gene, was predominant for isolates originating in the Japanese mainland. Type 1, CGA, type 2, CTA, and type 3 were detected from Korea, Indonesia, and Myanmar. No isolates with four copies of 6 bp were detected from Myanmar, Okinawa, and Japanese Brazilian patients. Type 4, TTC, with three copies of 6 bp, was detected only from Japanese Brazilians. The results indicate that infection occurred in Brazil and the disease developed later in Japan.</p>},
  year = {2006},
  journal = {FEMS microbiology letters},
  volume = {261},
  pages = {150-4},
  month = {2006 Aug},
  issn = {0378-1097},
  url = {http://onlinelibrary.wiley.com/doi/10.1111/j.1574-6968.2006.00346.x/pdf},
  doi = {10.1111/j.1574-6968.2006.00346.x},
  language = {eng},
}